Pregeb 150mg (Pregabalin 150 mg)

What is Pregeb 150mg?

Pregeb 150mg is a prescription medication that contains Pregabalin, a drug used primarily for treating neuropathic pain, epilepsy, and generalized anxiety disorder (GAD). Pregabalin is classified as an anticonvulsant and neuropathic pain agent. Pregeb is a brand name commonly available in India and other regions.

Uses of Pregeb 150mg

Pregeb 150mg is used for managing:

• Neuropathic pain, including:

  • Diabetic neuropathy

  • Post-herpetic neuralgia (after shingles)

  • Spinal cord injury-related nerve pain

• Fibromyalgia

• Partial-onset seizures (as adjunctive therapy)

• Generalized Anxiety Disorder (GAD) (approved in some countries)

Benefits of Pregeb 150mg

• Provides effective relief from chronic nerve pain

• Reduces the frequency and severity of partial seizures

• Improves sleep quality in patients with chronic pain

• Alleviates anxiety symptoms (when used for GAD)

• Enhances daily functioning and quality of life

How Does Pregeb 150mg Work?

Pregabalin binds to the α2-δ subunit of voltage-gated calcium channels in the central nervous system. This reduces the release of excitatory neurotransmitters like glutamate, norepinephrine, and substance P, resulting in:

• Decreased nerve signal transmission

• Pain relief

• Seizure control

• Anxiolytic (calming) effects

How to Take Pregeb 150mg

• Take the capsule whole with water.

• Can be taken with or without food.

• Take it at the same time each day.

• Do not stop abruptly; discontinue gradually under medical guidance to avoid withdrawal symptoms.

Dosage of Pregeb 150mg

• Typically prescribed once or twice daily depending on the condition.

• Initial dose: Usually 75 mg twice daily (150 mg/day), may be increased as needed.

• Maximum daily dose: Up to 600 mg/day (in divided doses), based on response.

• Renal impairment: Dose adjustment is necessary based on creatinine clearance.

Missed Dose and Overdose

Missed Dose:

• Take it as soon as you remember.

• If it’s close to the next dose, skip the missed one—do not double dose.

Overdose:

• Symptoms: Drowsiness, confusion, agitation, tremors, or seizures.

• In case of overdose, seek immediate medical attention.

Available Strengths of Pregeb

Pregeb is available in the following strengths:

• Pregeb 75mg

• Pregeb 150mg

• Pregeb 300mg

Side Effects of Pregeb 150mg

Common Side Effects:

• Dizziness

• Drowsiness

• Weight gain

• Swelling of hands/feet (edema)

• Blurred vision

• Dry mouth

Serious Side Effects:

• Allergic reactions (rash, swelling, difficulty breathing)

• Suicidal thoughts or behavior

• Muscle pain or weakness

• Severe drowsiness or confusion

Interactions of Pregeb 150mg

• Alcohol and CNS depressants (e.g., benzodiazepines, opioids): Increased risk of sedation and respiratory depression.

• ACE inhibitors: May increase the risk of angioedema.

• Thiazolidinediones (for diabetes): Can increase fluid retention.

• Be cautious with other drugs affecting renal function.

Precautions of Pregeb 150mg

• Use cautiously in patients with kidney disease.

• Avoid alcohol and heavy machinery until drug effects are known.

• Not recommended during pregnancy or breastfeeding unless prescribe.

• Monitor for mood changes or suicidal ideation.

• Gradual dose reduction is needed when discontinuing.

Storage Information

• Store at room temperature (15–25°C or 59–77°F).

• Keep away from heat and moisture.

• Keep out of reach of children and pets.

Availability in the US and Australia

• Pregeb is commonly sold in India and other countries.

• In the US and Australia, Pregabalin is marketed under brand names like:

  • Lyrica

  • Generic Pregabalin (available)

• Requires a prescription in both countries.

Frequently Asked Questions (FAQs)

1. Is Pregeb 150mg the same as Lyrica?

Yes. Both contain Pregabalin, though manufacture by different companies.

2. Can Pregeb 150mg be used for sleep?

It may improve sleep indirectly by reducing nerve pain or anxiety, but it is not a sleeping pill.

3. Is Pregabalin addictive?

Pregabalin can cause dependence in some individuals, especially when misused. Always use as directed.

4. How long does it take for Pregeb to work?

Initial relief can occur within a few days, but full benefits may take 1–2 weeks.

5. Can I stop taking Pregeb 150mg suddenly?

No. Sudden discontinuation can lead to withdrawal symptoms. Taper off gradually under a doctor supervision.