Indocap SR 75 mg (Indomethacin)

What is Indocap SR 75 mg (Indomethacin)?

Indocap SR 75 mg is a sustained-release capsule containing Indomethacin, a nonsteroidal anti-inflammatory drug (NSAID). It is used to relieve pain, inflammation, and swelling associated with a range of musculoskeletal and joint disorders. The SR (sustained release) formulation ensures a prolonged therapeutic effect and less frequent dosing.

Uses of Indocap SR 75 mg

Indocap SR 75 mg is commonly prescribed for:

• Rheumatoid arthritis

• Osteoarthritis

• Ankylosing spondylitis

• Gouty arthritis (acute gout flares)

• Bursitis and tendonitis

• Lower back pain

• Pain and inflammation after injury or surgery

Benefits of Indocap SR 75 mg

• Extended pain relief due to sustained-release action

• Reduces joint stiffness, swelling, and inflammation

• Improves mobility and quality of life in chronic inflammatory conditions

• Convenient once or twice-daily dosing compared to immediate-release formulations

How Does Indocap SR 75 mg Work?

Indomethacin works by blocking cyclooxygenase (COX-1 and COX-2) enzymes, which are involved in the synthesis of prostaglandins—chemical messengers that cause inflammation, pain, and fever. By inhibiting prostaglandin production, Indocap SR reduces pain and swelling.

How to Take Indocap SR 75 mg

• Take with food or milk to minimize gastrointestinal discomfort

• Swallow the capsule whole; do not chew or crush it

• Take it at the same time each day, preferably in the evening or as advised by your doctor

• Avoid alcohol to reduce the risk of stomach bleeding

Dosage of Indocap SR 75 mg

• Typical Adult Dose: One 75 mg capsule once or twice daily, depending on the severity of the condition

• Dosage is adjusted based on patient response and tolerability

• Do not exceed the maximum recommended daily dose (usually 150 mg/day) unless directed by a physician

Always follow your healthcare provider’s dosage instructions.

Missed Dose and Overdose

• Missed Dose: Take it as soon as you remember. If it’s almost time for the next dose, skip the missed one. Do not double the dose.

• Overdose: Symptoms may include nausea, vomiting, dizziness, drowsiness, stomach pain, or difficulty breathing. In case of suspected overdose, seek immediate medical help or contact a poison control center.

Available Strengths of Indocap (Indomethacin)

Indocap is available in different forms and strengths:

• Indocap 25 mg capsules (immediate-release)

• Indocap SR 75 mg capsules (sustained-release)

• Indocap suppositories (rectal)

• Indomethacin injection (hospital use only)

Side Effects of Indocap SR 75 mg

Common Side Effects:

• Nausea, vomiting

• Stomach pain or discomfort

• Heartburn or indigestion

• Dizziness or headache

• Drowsiness

Serious Side Effects (seek medical attention):

• Gastrointestinal bleeding or ulcers

• High blood pressure

• Kidney or liver dysfunction

• Allergic reactions (rash, swelling, breathing difficulty)

• Increased risk of heart attack or stroke with prolonged use

Interactions of Indocap SR 75 mg

Indomethacin may interact with:

• Other NSAIDs or corticosteroids – increased risk of ulcers or bleeding

• Anticoagulants (e.g., warfarin) – increased bleeding risk

• Diuretics and antihypertensives – reduced effectiveness and kidney stress

• Lithium – may increase lithium toxicity

• Methotrexate – may enhance toxicity

• SSRIs – may increase GI bleeding risk

Always inform your doctor about all medications, supplements, or herbal products you are taking.

Precautions of Indocap SR 75 mg

• Avoid in pregnancy, especially the third trimester, unless clearly needed

• Caution in breastfeeding – consult your doctor

• History of ulcers, bleeding, heart disease, kidney or liver issues – use only under strict medical supervision

• Avoid driving or operating machinery if you feel dizzy or drowsy

Storage Information

• Store below 25°C (77°F) in a dry place

• Protect from moisture and direct sunlight

• Keep out of reach of children

• Do not use after the expiration date on the label

Availability in the US and Australia

• United States: Indomethacin is available in both immediate and extended-release forms. Brand names may vary; Indocap SR specifically may not be marketed under this name.

• Australia: Indocap SR 75 mg is available by prescription only. Other formulations of Indomethacin are also available.

Frequently Asked Questions (FAQs)

1. What is the difference between Indocap and Indocap SR?

Indocap is the immediate-release version (usually 25 mg), while Indocap SR is a sustained-release 75 mg capsule, offering longer-lasting relief with less frequent dosing.

2. Can I take Indocap SR 75 mg for a headache?

It is not typically used for mild headaches. Indocap SR is prescribed for more severe, inflammatory pain like arthritis or gout.

3. How long does it take for Indocap SR to work?

It may take 1–2 hours to start relieving symptoms. Full anti-inflammatory effects may take a few days of consistent use.

4. Is it safe for long-term use?

Long-term use should be closely monitored due to the risk of side effects like ulcers, kidney damage, and heart issues.

5. Can I take Indocap SR with paracetamol?

Yes, they can be used together as they work through different mechanisms, but always under medical guidance.